Phenotypes for Atm Rad50 MGI:5614078 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Atm^tm1Awb/Atm^tm1Awb Rad50^tm4.1Jpt/Rad50⁺
Genetic Background	involves: 129/Sv * 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atm^tm1Awb mutation (7 available); any Atm mutation (167 available)
Rad50^tm4.1Jpt mutation (0 available); any Rad50 mutation (53 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased tumor latency ( J:209141 )

• marked increase in the latency of thymic lymphomas compared to mutant mice wild-type for Rad50

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24