Phenotypes Associated with This Genotype

Genotype
MGI:5613966

• Allelic Composition: Tek^tm1.1Vlcg/Tek^tm1.1Vlcg; Gt(ROSA)26Sor^{tm1(rtTA,EGFP)Nagy}/?; Tg(tetO-cre)1Jaw/0
• Genetic Background: involves: 129 * C57BL/6NCr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal anterior eye segment morphology ( J:217296 )

• in mice exposed to deoxycycline treatment at E16.5

increased cornea size ( J:217296 )

• enlarged

increased eye anterior chamber depth ( J:217296 )

• increased anterior chamber depth

buphthalmos ( J:217296 )

• eyes begin to protrude by 21 to 28 days of age in mice exposed to deoxycycline treatment at E16.5

• difficulty closing eyelids by 8 weeks of age