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Phenotypes Associated with This Genotype
Genotype
MGI:5613410
Allelic
Composition
Or2b4tm5(cre)Mom/Or2b4+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or2b4tm5(cre)Mom mutation (1 available); any Or2b4 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• Like other null alleles of this olfactory receptor, the olfactory sensory neurons of the sensory organ are found predominantly in the basal, not apical, sensory organ epithelium and main olfactory epithelium
• olfactory sensory neurons that transcribe this locus express nuclear localized Cre recombinase rather than the endogenous olfactory receptor

taste/olfaction
• Like other null alleles of this olfactory receptor, the olfactory sensory neurons of the sensory organ are found predominantly in the basal, not apical, sensory organ epithelium and main olfactory epithelium
• olfactory sensory neurons that transcribe this locus express nuclear localized Cre recombinase rather than the endogenous olfactory receptor

craniofacial
• Like other null alleles of this olfactory receptor, the olfactory sensory neurons of the sensory organ are found predominantly in the basal, not apical, sensory organ epithelium and main olfactory epithelium
• olfactory sensory neurons that transcribe this locus express nuclear localized Cre recombinase rather than the endogenous olfactory receptor

respiratory system
• Like other null alleles of this olfactory receptor, the olfactory sensory neurons of the sensory organ are found predominantly in the basal, not apical, sensory organ epithelium and main olfactory epithelium
• olfactory sensory neurons that transcribe this locus express nuclear localized Cre recombinase rather than the endogenous olfactory receptor

growth/size/body
• Like other null alleles of this olfactory receptor, the olfactory sensory neurons of the sensory organ are found predominantly in the basal, not apical, sensory organ epithelium and main olfactory epithelium
• olfactory sensory neurons that transcribe this locus express nuclear localized Cre recombinase rather than the endogenous olfactory receptor


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory