Analysis Tools
cardiovascular system
|
• increased cross-sectional area at 5 weeks of age
|
|
• at 13 weeks of age
|
|
• decreased LV diastolic posterior wall thickness at 13 weeks of age
|
|
• diffuse interstitial fibrosis in both the atria and ventricles at 13 weeks of age
|
|
• maximal rates of systolic pressure increase are significantly lower compared to controls at 13 weeks of age
|
|
• in most mice at 12 weeks of age
|
|
• in 16 of 38 mice at up to 20 weeks of age
|
|
• in 2 of 12 mice at 9 and 12 weeks of age
|
|
• complete AV block in 1 of 12 mice at 9 and 12 weeks of age
|
|
• in most mice at 9 and 12 weeks of age
|
homeostasis/metabolism
|
• large organized thrombus in the left atrium at 13 weeks of age
|
muscle
|
• increased cross-sectional area at 5 weeks of age
|
cellular
|
• diffuse interstitial fibrosis in both the atria and ventricles at 13 weeks of age
|
