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Phenotypes Associated with This Genotype
Genotype
MGI:5604147
Allelic
Composition		 Rag1tm1(GFP)Imku/?
Zfp335blt/Zfp335blt
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag1tm1(GFP)Imku mutation (0 available); any Rag1 mutation (132 available)
Zfp335blt mutation (1 available); any Zfp335 mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal CD4-positive T cell differentiation ( J:214793 )
• high rate of decay of recent thymic emigrants (RTE) in spleen and lymph nodes as compared to heterozygous controls, suggesting a block in post-thymic naive T cell maturation

immune system
abnormal CD4-positive T cell differentiation ( J:214793 )
• high rate of decay of recent thymic emigrants (RTE) in spleen and lymph nodes as compared to heterozygous controls, suggesting a block in post-thymic naive T cell maturation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory