Phenotypes Associated with This Genotype

Genotype
MGI:5604141

• Allelic Composition: \Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
• Genetic Background: involves: CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

decreased diameter of tibia ( J:211171 )

• tibias are about 25% narrower at the mid-diaphysis compared to wild-type mice

short tibia ( J:211171 )

• about 7% decrease in tibia length

skeleton

decreased diameter of tibia ( J:211171 )

• tibias are about 25% narrower at the mid-diaphysis compared to wild-type mice

short tibia ( J:211171 )

• about 7% decrease in tibia length

decreased trabecular bone volume ( J:211171 )

• trabecular bone volume in the metaphysis is reduced by about 36%, although this doesnt reach statistical significance

increased compact bone thickness ( J:211171 )

• cortical thickness is increased by about 14.5%