craniofacial
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• reduced size of frontal bones at E18.5, leading to a gap between the left and right frontal bones
|
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• reduced size of nasal bones at E18.5
|
|
• fusion of the nasal capsule is nearly complete at E18.5 although not phenotypically normal
|
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• palate formation is improved compared to heterozygous Hand1tm3Abfi Tg(Wnt1-cre)2Sor mice
|
digestive/alimentary system
|
• palate formation is improved compared to heterozygous Hand1tm3Abfi Tg(Wnt1-cre)2Sor mice
|
growth/size/body
|
• reduced size of frontal bones at E18.5, leading to a gap between the left and right frontal bones
|
|
• reduced size of nasal bones at E18.5
|
|
• fusion of the nasal capsule is nearly complete at E18.5 although not phenotypically normal
|
|
• palate formation is improved compared to heterozygous Hand1tm3Abfi Tg(Wnt1-cre)2Sor mice
|
respiratory system
|
• reduced size of nasal bones at E18.5
|
|
• fusion of the nasal capsule is nearly complete at E18.5 although not phenotypically normal
|
skeleton
|
• reduced size of frontal bones at E18.5, leading to a gap between the left and right frontal bones
|
|
• reduced size of nasal bones at E18.5
|
|
• fusion of the nasal capsule is nearly complete at E18.5 although not phenotypically normal
|


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