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Phenotypes Associated with This Genotype
Genotype
MGI:5588152
Allelic
Composition		 Gt(ROSA)26Sortm8(Map2k1*,-EGFP)Rsky/?
Tg(Dhh-cre)1Mejr/0
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm8(Map2k1*,-EGFP)Rsky mutation (1 available); any Gt(ROSA)26Sor mutation (1062 available)
Tg(Dhh-cre)1Mejr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:207470 )
N
• rarely observe aberrantly myelinated small axons in mutants and the ratio of nonmyelinated to myelinated axons is unchanged

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory