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Phenotypes Associated with This Genotype
Genotype
MGI:5586991
Allelic
Composition		 Gt(ROSA)26Sortm3.1(CAG-SORL1)Tew/Gt(ROSA)26Sor+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3.1(CAG-SORL1)Tew mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal nervous system morphology ( J:213687 )
• mice show reduced concentrations of murine amyloid beta40 and amyloid beta42 peptides
• however, concentration of the soluble murine APP alpha is not affected

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory