Phenotypes Associated with This Genotype

Genotype
MGI:5586504

• Allelic Composition: Col1a1^{tm2(tetO-Fosl2,-DsRed)Wag}/Col1a1⁺; Tg(Cebpb-tTA)5Bjd/0
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * NMRI

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

liver/biliary system

decreased liver triglyceride level ( J:210545 )

• compared with control mice when fed a high fat diet

decreased susceptibility to diet-induced hepatic steatosis ( J:210545 )

• mice fed a high fat diet do not develop steatohepatitis unlike control mice

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:213764 )

N • mice subjected to acetaminophen-induced hepatotoxicity exhibit a normal response

decreased liver triglyceride level ( J:210545 )

• compared with control mice when fed a high fat diet