Analysis Tools
growth/size/body
|
• in mice exposed to DCC
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mortality/aging
| N |
• mice are viable
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homeostasis/metabolism
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• in mice exposed to DCC
|
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• mild in mice fed a high fat diet
|
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• mild in mice fed a high fat diet
|
|
• compared with control mice when fed a high fat diet
(J:210545)
• reversion of high fat diet-induced elevations in alanine transaminase level following withdrawal of doxycycline
(J:210545)
• in mice exposed to DCC
(J:213764)
|
|
• slightly worse than in control mice fed a high fat diet
|
|
• slightly worse than in control mice when fed a high fat diet
|
|
• relative to body weight in mice exposed to DCC compared with control mice
|
|
• compared with control mice when fed a high fat diet
• reversion of high fat diet-induced steatosis following withdrawal of doxycycline
• however, adenorival Pparg restores diet-induced steatosis
|
|
• mice exposed to DCC exhibit reduced liver damage (increased relative liver weight and reduced ALT levels) compared with control mice
• mice subjected to acetaminophen-induced hepatotoxicity exhibit reduced liver damage compared with control mice
|
liver/biliary system
| N |
• mice exhibit no signs of liver fibrosis and serum parameters
|
|
• reduced compared with control mice fed a high fat diet
|
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• less pale livers with a reduction in lipid droplets than in control mice when a high fat diet
|
|
• in mice exposed to DCC
|
|
• compared with control mice when fed a high fat diet
• reversion of high fat diet-induced steatosis following withdrawal of doxycycline
• however, adenorival Pparg restores diet-induced steatosis
|
|
• compared with control mice when fed a high fat diet
• in mice fed a high fat diet following withdrawal of doxycycline
|
|
• reduction in lipid droplets compared with control mice when fed a high fat diet
• reversion of high fat diet-induced steatosis following doxycycline treatment
• however, adenorival Pparg restores diet-induced steatosis
|
immune system
|
• reduced compared with control mice fed a high fat diet
|
