Phenotypes Associated with This Genotype

Genotype
MGI:5583880

• Allelic Composition: Dsel^tm1Mmac/Dsel^tm1Mmac
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal mineral level ( J:213195 )

• reduced iduronic acid content in the brain and kidney chondroitin sulfate/dermatan sulfate (CS/DS)

abnormal enzyme/coenzyme activity ( J:213195 )

• reduced epimerase activity in the skin, lung, liver, spleen, kidney and brain

nervous system

nervous system phenotype ( J:213195 )

N • brains exhibit normal extracellular matrix