Phenotypes Associated with This Genotype

Genotype
MGI:5582906

• Allelic Composition: Cd22^tm2Tft/Cd22^tm2Tft
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased activation-induced B cell apoptosis ( J:208364 )

decreased B cell proliferation ( J:208364 )

• of stimulated cells

decreased B cell number ( J:208364 )

• in the spleen

abnormal peripheral B cell anergy ( J:208364 )

• in the spleen

cellular

increased activation-induced B cell apoptosis ( J:208364 )

decreased B cell proliferation ( J:208364 )

• of stimulated cells

hematopoietic system

increased activation-induced B cell apoptosis ( J:208364 )

decreased B cell proliferation ( J:208364 )

• of stimulated cells

decreased B cell number ( J:208364 )

• in the spleen