Phenotypes Associated with This Genotype

Genotype
MGI:5582621

• Allelic Composition: Grk5^tm2Rjl/Grk5^tm2Rjl; Tg(Myh6-cre)2182Mds/0
• Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiac hypertrophy ( J:212635 )

• 12 weeks after transaortic constriction, mice exhibit attenuated cardiac hypertrophy compared with wild-type mice

decreased response of heart to induced stress ( J:212635 )

• 12 weeks after transaortic constriction, mice exhibit attenuated cardiac hypertrophy with no increase in left ventricular dilatation and no change in ejection fraction compared with wild-type mice

homeostasis/metabolism

decreased response of heart to induced stress ( J:212635 )

• 12 weeks after transaortic constriction, mice exhibit attenuated cardiac hypertrophy with no increase in left ventricular dilatation and no change in ejection fraction compared with wild-type mice

growth/size/body

cardiac hypertrophy ( J:212635 )

• 12 weeks after transaortic constriction, mice exhibit attenuated cardiac hypertrophy compared with wild-type mice