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Phenotypes Associated with This Genotype
Genotype
MGI:5581638
Allelic
Composition		 Cables1Tg(CAG-rtTA,CAG-tTS)138Utr/Cables1Tg(CAG-rtTA,CAG-tTS)138Utr
Genetic
Background		 CAJcl.Cg-Cables1Tg(CAG-rtTA,CAG-tTS)138Utr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cables1Tg(CAG-rtTA,CAG-tTS)138Utr mutation (1 available); any Cables1 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal CNS glial cell morphology ( J:167073 )
• disruption of the dorsal midline zipper glia (MZG) but not of the ventral MZG in forebrains at E18.5
absent corpus callosum ( J:167073 )
• agenesis in all homozygous mice, which was accompanied by the formation of Probst bundles

cellular
abnormal CNS glial cell morphology ( J:167073 )
• disruption of the dorsal midline zipper glia (MZG) but not of the ventral MZG in forebrains at E18.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory