Analysis Tools
liver/biliary system
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• 5-fold increase in the production of hepatic DNA adducts in mice treated with methyleugenol
• 8-fold increase in the levels of hepatic N2-MIE-dG adducts in mice treated with 1OH-ME
• at low doses of methyleugenol, mice exhibit a somewhat supralinear in the dose-relationship for the formation of hepatic DNA adducts compared with wild-type mice
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