Phenotypes for Tmem127 MGI:5581338 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Tmem127^tm1.1Pdah/Tmem127^tm1.1Pdah
Genetic Background	involves: BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem127^tm1.1Pdah mutation (0 available); any Tmem127 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal cell morphology ( J:209071 )

• higher number of late endosomal and lysosomal vesicles in mouse embryonic fibroblasts

abnormal lysosome physiology ( J:209071 )

• increased lysosomal mass in mouse embryonic fibroblasts

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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