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Phenotypes Associated with This Genotype
Genotype
MGI:5578645
Allelic
Composition		 Tmprss2tm1.1(ERG)Sho/Tmprss2tm1.1(ERG)Sho
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmprss2tm1.1(ERG)Sho mutation (0 available); any Tmprss2 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:212219 )
N
• prostates are largely normal and do not develop prostatic intraepithelial neoplasia (PIN) lesions or cancer
• prostate cell testosterone levels are normal in castrated and non-castrated mice

neoplasm
neoplasm ( J:212219 )
N
• prostates are largely normal and do not develop prostatic intraepithelial neoplasia (PIN) lesions or cancer

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/31/2026
MGI 6.24 		The Jackson Laboratory