Phenotypes Associated with This Genotype

Genotype
MGI:5577255

• Allelic Composition: Elfn1^{tm1(KOMP)Vlcg}/Elfn1^{tm1(KOMP)Vlcg}
• Genetic Background: involves: C57BL/6NTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:209758 )

N • normal gross neuronal connectivity in brain sections and innervation of the stria medullaris and fasciculus retroflexus

seizures ( J:209758 )

• in some mice during routine cage changers between 4 and 9 months old

behavior/neurological

decreased anxiety-related response ( J:209758 )

• during open field behavioral testing

impaired coordination ( J:209758 )

• less animals complete and take longer to complete the wire-hang test

decreased grip strength ( J:209758 )

• less animals complete and take longer to complete the wire-hang test

hyperactivity ( J:209758 )

♂ • between the ages 2 to 4 months old, can be attenuated with stimulant medication amphetamine

seizures ( J:209758 )

• in some mice during routine cage changers between 4 and 9 months old