Phenotypes Associated with This Genotype

Genotype
MGI:5576900

• Allelic Composition: Ppargc1a^tm2Brsp/Ppargc1a⁺; Tg(Myog-cre)1Eno/0
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:127403 )

N • mice fed a high fat diet exhibit normal heat production and oxygen consumption

increased circulating glucose level ( J:127403 )

• in mice fed a high fat diet

• however, mice fed standard chow exhibit normal glucose serum levels

increased circulating interleukin-6 level ( J:127403 )

impaired glucose tolerance ( J:127403 )

• in mice fed standard chow or a high fat diet

immune system

increased circulating interleukin-6 level ( J:127403 )

behavior/neurological

behavior/neurological phenotype ( J:127403 )

N • mice fed a high fat diet exhibit normal food intake

growth/size/body

growth/size/body region phenotype ( J:127403 )

N • mice fed standard chow or a high fat diet exhibit normal body weight and composition