homeostasis/metabolism
N |
• mice fed standard chow or a high fat diet exhibit normal insulin tolerance
• hepatic glucose output under basal and clamped conditions is normal
|
• in mice fed a high fat diet
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• in mice fed a high fat diet
|
• in mice fed a high fat diet
|
• mice exhibit increased systemic glucose uptake and glycolysis compared with control mice
• however, glycogen synthesis is normal
|
• in fed mice on standard chow
• however, fasted mice exhibit normal blood glucose levels
|
• in fasted and fed mice on a high fat diet
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• in fed mice on standard chow or a high fat diet
|
• in fed mice on a high fat diet
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• in mice fed a high fat diet
|
endocrine/exocrine glands
N |
• islets exhibit normal basal and glucose-stimulated insulin secretion
|
• reduced cell size
|
growth/size/body
• in mice fed standard chow or a high fat diet
|
• in mice fed a high fat diet
|
immune system
adipose tissue
• in mice fed standard chow or a high fat diet
|
cellular
• decreased function as measured by Cox and succinate dehydrogenase activity
|
behavior/neurological
• during the day and night in mice fed a high fat diet
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