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Phenotypes Associated with This Genotype
Genotype
MGI:5576877
Allelic
Composition		 Prdm6tm1.1Jrld/Prdm6tm1.2Jrld
Tg(Tagln-cre)1Her/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm6tm1.1Jrld mutation (1 available); any Prdm6 mutation (26 available)
Prdm6tm1.2Jrld mutation (0 available); any Prdm6 mutation (26 available)
Tg(Tagln-cre)1Her mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Massive hemorrhage in Prdm6tm1.1Jrld/Prdm6tm1.2Jrld; Tg(Tagln-cre)1Her lungs

mortality/aging
postnatal lethality, complete penetrance ( J:209773 )
• newborn mice die within 2 days after birth
neonatal lethality, incomplete penetrance ( J:209773 )
• newborn mice die within 2 days after birth

cardiovascular system
lung hemorrhage ( J:209773 )
• massive

respiratory system
lung hemorrhage ( J:209773 )
• massive

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory