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Phenotypes Associated with This Genotype
Genotype
MGI:5576780
Allelic
Composition		 Ros1tm1.1Char/Ros1tm1.1Char
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ros1tm1.1Char mutation (0 available); any Ros1 mutation (148 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
asthenozoospermia ( J:211844 )
• decreased progressive and total motility
abnormal epididymis epithelium morphology ( J:211844 )
• impaired initial segment epithelia differentiation

cellular
asthenozoospermia ( J:211844 )
• decreased progressive and total motility

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory