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Phenotypes Associated with This Genotype
Genotype
MGI:5576702
Allelic
Composition		 Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze/Gt(ROSA)26Sor+
Shox2tm1.1(cre)Oki/Shox2+
Genetic
Background		 involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm39.1(CAG-hop/EYFP)Hze mutation (0 available); any Gt(ROSA)26Sor mutation (1098 available)
Shox2tm1.1(cre)Oki mutation (0 available); any Shox2 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal nervous system physiology ( J:209344 )
• electrical stimulation of spinal cords to induce locomotor activity is decreased by about 25% when Shox2 interneurons are inactivated by light, which is similar to the phenotype observed when the population of Shox2 interneurons is ablated

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory