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Phenotypes Associated with This Genotype
Genotype
MGI:5575487
Allelic
Composition
Kcnk2tm1Lex/Kcnk2tm1Lex
Genetic
Background
involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk2tm1Lex mutation (1 available); any Kcnk2 mutation (34 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
N
• mice exhibit normal heart rate, blood pressure, pulse wave velocity, peak blood flow velocities, middle cerebral artery endothelium-mediated dilation, NO and cyclooxygenase-dependent components in the basilar arteries, alpha-linolenic acid-induced basilar artery dilation, and alpha-linoleic acid or arachidonic acid increase in whole cell currents in cerebrovascular smooth muscle cells


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory