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Phenotypes Associated with This Genotype
Genotype
MGI:5574077
Allelic
Composition		 Cdkl5tm1.2Cogr/Cdkl5+
Tg(Thy1-YFP)#Jrs/0
Genetic
Background		 involves: 129P2/OlaHsd * 129S/Sv * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkl5tm1.2Cogr mutation (2 available); any Cdkl5 mutation (20 available)
Tg(Thy1-YFP)#Jrs mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
thin cerebral cortex ( J:209635 )
• intermediate
abnormal dendrite morphology ( J:209635 )
• intermediate reduction in total length of apical dendritic arbors of cortical and hippocampal pyramidal neurons with bimodal distribution

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory