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Phenotypes Associated with This Genotype
Genotype
MGI:5569535
Allelic
Composition
Tg(CMV-HTT*48Q)BTag/Tg(CMV-HTT*48Q)BTag
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• begins at 16 weeks of age
• begins at 16 weeks of age
• begins at 16 weeks of age
• 8 of 24 mice show stereotypy beginning at 16 weeks of age, consisting of generalized hyperactive behavior, including unidirectional rotations, backflips, and excessive grooming

nervous system
• approximately 20% fewer small and medium neurons in the striata
• neuronal loss is also seen in the hippocampus, thalamus, cerebral cortex, and cerebellum

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Huntington's disease DOID:12858 OMIM:143100
J:50173


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory