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Phenotypes Associated with This Genotype
Genotype
MGI:5569383
Allelic
Composition		 Rb1cc1tm1.1Guan/Rb1cc1tm1.1Guan
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1cc1tm1.1Guan mutation (0 available); any Rb1cc1 mutation (82 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
abnormal enterocyte morphology ( J:206181 )
• following delivery of a Tat-cre, colonic epithelial spheroids exhibit increased mucin accumulation compared with control cells
• spheroids exhibit reduced calcium levels compared with wild-type spheroids

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory