Phenotypes Associated with This Genotype

Genotype
MGI:5568955

• Allelic Composition: Setd1b^tm1.1Afst/Setd1b^tm1.1Afst
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:208420 )

• by E11.5

embryo

embryonic growth retardation ( J:208420 )

• from E7.5 until embryos died at ~E11.5

growth/size/body

embryonic growth retardation ( J:208420 )

• from E7.5 until embryos died at ~E11.5

cellular

cellular phenotype ( J:208420 )

N • at E10.5 global H3K4 methylation is not affected