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Phenotypes Associated with This Genotype
Genotype
MGI:5568400
Allelic
Composition		 Egln1tm1.1Brei/Egln1tm1.1Brei
Epas1tm1Mcs/Epas1tm1Mcs
Tg(CD68-icre)1Bwlx/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egln1tm1.1Brei mutation (0 available); any Egln1 mutation (23 available)
Epas1tm1Mcs mutation (1 available); any Epas1 mutation (66 available)
Tg(CD68-icre)1Bwlx mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:194598 )
N
• no premature death is observed

hematopoietic system
hematopoietic system phenotype ( J:194598 )
N
• erythropoiesis phenotype seen in Phd2 single mutants is absent from double mutants
decreased hematocrit ( J:194598 )
• HCT is lower than wild type
decreased hemoglobin content ( J:194598 )
• lower than in wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory