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Phenotypes Associated with This Genotype
Genotype
MGI:5568215
Allelic
Composition
Mecp2tm1.1Jtc/Mecp2tm1.1Jtc
Genetic
Background
involves: 129S6/SvEvTac * 129/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2tm1.1Jtc mutation (1 available); any Mecp2 mutation (46 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• female mice exhibit hindlimb clasping by 6 months of age

mortality/aging
• most females die before a year, however, some females survive to more than a year
• lifespan is longer than in males

respiratory system
• female mice exhibit breathing irregularities by 6 months of age


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory