Phenotypes Associated with This Genotype

Genotype
MGI:5566905

• Allelic Composition: Pcdh15^tm1.1Ugds/Pcdh15^tm1.1Ugds; Myo15a^{tm1.1(cre)Ugds}/Myo15a⁺
• Genetic Background: involves: 129S1/SvImJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal cochlear hair bundle tip links morphology ( J:209275 )

short inner hair cell stereocilia ( J:209275 )

decreased inner hair cell stereocilia number ( J:209275 )

abnormal outer hair cell stereociliary bundle morphology ( J:209275 )

short outer hair cell stereocilia ( J:209275 )

decreased outer hair cell stereocilia number ( J:209275 )

abnormal hair cell mechanoelectric transduction ( J:209275 )

abnormal auditory brainstem response ( J:209275 )

increased or absent threshold for auditory brainstem response ( J:209275 )

abnormal cochlear nerve compound action potential ( J:209275 )

deafness ( J:209275 )

nervous system

abnormal cochlear hair bundle tip links morphology ( J:209275 )

short inner hair cell stereocilia ( J:209275 )

decreased inner hair cell stereocilia number ( J:209275 )

abnormal outer hair cell stereociliary bundle morphology ( J:209275 )

short outer hair cell stereocilia ( J:209275 )

decreased outer hair cell stereocilia number ( J:209275 )

abnormal hair cell mechanoelectric transduction ( J:209275 )

abnormal cochlear nerve compound action potential ( J:209275 )