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Phenotypes Associated with This Genotype
Genotype
MGI:5565190
Allelic
Composition		 Cd79am1Anu/Cd79am1Anu
Rasgrp1m1Anu/Rasgrp1m1Anu
Genetic
Background		 involves: C57BL/6JSfdAnu * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79am1Anu mutation (3 available); any Cd79a mutation (26 available)
Rasgrp1m1Anu mutation (2 available); any Rasgrp1 mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:207898 )
N
• profoundly suppressed accumulation of PD1+ Helios+ CD4+ T cells compared with Rasgrp1m1Anu homozygotes
• restored number of effector/memory and regulatory CD4+ T cells compared with Rasgrp1m1Anu homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory