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Phenotypes Associated with This Genotype
Genotype
MGI:5563673
Allelic
Composition		 Il1atm1Yiw/Il1atm1Yiw
Il1btm1Yiw/Il1btm1Yiw
Tg(KRT14-CASP1)1Miz/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il1atm1Yiw mutation (0 available); any Il1a mutation (30 available)
Il1btm1Yiw mutation (0 available); any Il1b mutation (23 available)
Tg(KRT14-CASP1)1Miz mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
dermatitis ( J:78602 )
• late onset of skin alterations which are similar to, but milder than, in single Tg(KRT14-CASP1)1Miz mutants

integument
dermatitis ( J:78602 )
• late onset of skin alterations which are similar to, but milder than, in single Tg(KRT14-CASP1)1Miz mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory