mortality/aging
N |
• viable
|
nervous system
• cells spread less when plated on laminin compared to wild-type cells
|
• 5% of axons in the sciatic nerve have overly thin myelin for the caliber of the axon
|
• 25% of axons in the sciatic nerve have overly thick myelin for the caliber of the axon
|
• in the sciatic nerve, remak bundles contain axons that are greater than 1 um in diameter suggesting a defect in recognition or sorting of axons
• other large caliber axons in the sciatic nerve are sorted properly but not myelinated suggesting a delay in myelination
• some small caliber axons (less than 1 um in diameter) in the sciatic nerve are abnormally myelinated
• 5% of axons in the sciatic nerve have overly thin myelin for the caliber of the axon
|
• occasional
|
• in the sciatic nerve, remak bundles contain axons that are greater than 1 um in diameter suggesting a defect in recognition or sorting of axons
• other large caliber axons in the sciatic nerve are sorted properly but not myelinated suggesting a delay in myelination
• some small caliber axons (less than 1 um in diameter) in the sciatic nerve are abnormally myelinated
• 5% of axons in the sciatic nerve have overly thin myelin for the caliber of the axon
|
• 25% of axons in the sciatic nerve have overly thick myelin for the caliber of the axon
|
cellular
• cells spread less when plated on laminin compared to wild-type cells
|