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Phenotypes Associated with This Genotype
Genotype
MGI:5562713
Allelic
Composition		 Bak1tm1Thsn/Bak1tm1Thsn
Baxtm2Sjk/Baxtm2Sjk
Tg(Lck-cre)548Jxm/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bak1tm1Thsn mutation (2 available); any Bak1 mutation (26 available)
Baxtm2Sjk mutation (1 available); any Bax mutation (24 available)
Tg(Lck-cre)548Jxm mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased regulatory T cell number ( J:208318 )
• at 15 months as in Bcl2l11tm1.1Ast homozygotes

hematopoietic system
increased regulatory T cell number ( J:208318 )
• at 15 months as in Bcl2l11tm1.1Ast homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory