About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5562539
Allelic
Composition
Sema6aGt(KST069)Byg/Sema6aGt(KST069)Byg
Tg(Trhr-EGFP)HU193Gsat/0
Genetic
Background
involves: 129P2/OlaHsd * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sema6aGt(KST069)Byg mutation (1 available); any Sema6a mutation (82 available)
Tg(Trhr-EGFP)HU193Gsat mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• cell patch recording of direction-selective ganglion cells presented with drifting-bar motion stimulation show that On direction-selective tuning is compromised; however, Off response is similar to controls
• On responses have abnormal, broader, directional tuning, with the magnitudes of the response vector sums being significantly lower


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory