Phenotypes Associated with This Genotype

Genotype
MGI:5561396

• Allelic Composition: b2b2588Clo/b2b2588Clo
• Genetic Background: C57BL/6J-b2b2588Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2588-003-2 (E16.5) presents with right aortic arch and parallel outflow tracts, shown to be DORV by EFIC imaging

cardiovascular system

abnormal aortic arch morphology ( J:175213 )

right aortic arch ( J:175213 )

abnormal left subclavian artery morphology ( J:175213 )

double outlet right ventricle ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

atrioventricular septal defect ( J:175213 )

ventricular septal defect ( J:175213 )

craniofacial

cleft palate ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

growth/size/body

cleft palate ( J:175213 )

herniated abdominal wall ( J:175213 )

omphalocele ( J:175213 )

kidney cyst ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

renal/urinary system

kidney cyst ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )