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Phenotypes Associated with This Genotype
Genotype
MGI:5559492
Allelic
Composition
Slx4tm1.2Jrou/Slx4tm1.2Jrou
Genetic
Background
B6.129P2-Slx4tm1.2Jrou
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slx4tm1.2Jrou mutation (0 available); any Slx4 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are obtained at E13.5
• fewer than expected mice are obtained at weaning

reproductive system
• at 10 weeks

cellular
• in mouse embryonic fibroblasts treated with DNA interstrand crosslinking agents (nitrogen mustard and MMC)
• chromatid breaks and radial structures in MMC-treated mouse embryonic fibroblasts

endocrine/exocrine glands
• at 10 weeks

homeostasis/metabolism


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory