Mouse Genome Informatics
tg
    Tg(Thy1-APPSweAut)A7Tiwa/0
Not Specified
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• develop progressive amyloid deposition in cerebral cortices at around 9-12 months of age
• young (4 month) mutants treated with the anti-amyloid beta antibody 266 exhibit increased levels of monomer amyloid beta species in an antibody-bound form, without affecting that of total amyloid beta

homeostasis/metabolism
• develop progressive amyloid deposition in cerebral cortices at around 9-12 months of age
• young (4 month) mutants treated with the anti-amyloid beta antibody 266 exhibit increased levels of monomer amyloid beta species in an antibody-bound form, without affecting that of total amyloid beta

Mouse Models of Human Disease
OMIM IDRef(s)
Alzheimer Disease; AD 104300 J:204270