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Phenotypes Associated with This Genotype
Genotype
MGI:5556401
Allelic
Composition		 Terctm1Rdp/Terctm1Rdp
Tinf2tm2.2Tdl/Tinf2+
Genetic
Background		 involves: 129 * BALB/cJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Terctm1Rdp mutation (4 available); any Terc mutation (8 available)
Tinf2tm2.2Tdl mutation (0 available); any Tinf2 mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal chromosome morphology ( J:207367 )
• increase in chromosome ends without telomeric signals or signal loss from one of two sisters
decreased telomere length ( J:207367 )
• telomeres in bone marrow are shorter than homozygous Terctm1Rdp controls
• class of telomeres shorter than 15 kb is increased, while subfraction of longer telomeres is decreased

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory