Phenotypes Associated with This Genotype

Genotype
MGI:5556058

• Allelic Composition: Tspan2^tm1Hbw/Tspan2^tm1Hbw
• Genetic Background: C57BL/6-Tspan2^tm1Hbw

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:201143 )

N • myelination and myelin thickness are similar to wild-type controls

N • no axonal pathology is detected

astrocytosis ( J:201143 )

• very mild astrogliosis in the hippocampal fimbria

microgliosis ( J:201143 )

• low grade in the hippocampal fimbria

behavior/neurological

behavior/neurological phenotype ( J:201143 )

N • no gross motor impairments detected

growth/size/body

growth/size/body region phenotype ( J:201143 )

N • similar to controls at 4 and 40 weeks of age

hematopoietic system

microgliosis ( J:201143 )

• low grade in the hippocampal fimbria

immune system

microgliosis ( J:201143 )

• low grade in the hippocampal fimbria

cellular

astrocytosis ( J:201143 )

• very mild astrogliosis in the hippocampal fimbria

microgliosis ( J:201143 )

• low grade in the hippocampal fimbria