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Phenotypes Associated with This Genotype
Genotype
MGI:5554380
Allelic
Composition		 Rasal2Gt(463C12)Cmhd/Rasal2Gt(463C12)Cmhd
Tg(MMTVneu)202Mul/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rasal2Gt(463C12)Cmhd mutation (0 available); any Rasal2 mutation (61 available)
Tg(MMTVneu)202Mul mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased mammary adenocarcinoma incidence ( J:202603 )
• at the same frequency as in Tg(MMTVneu)202Mul mice
increased metastatic potential ( J:202603 )
• increased metastasis to additional organs compared with Tg(MMTVneu)202Mul mice

endocrine/exocrine glands
increased mammary adenocarcinoma incidence ( J:202603 )
• at the same frequency as in Tg(MMTVneu)202Mul mice

integument
increased mammary adenocarcinoma incidence ( J:202603 )
• at the same frequency as in Tg(MMTVneu)202Mul mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory