Phenotypes Associated with This Genotype

Genotype
MGI:5553173

• Allelic Composition: Helq^{Gt(RRF112)Byg}/Helq⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal ovary morphology ( J:206104 )

♀ • luteinized stroma in 2 of 7 mice

decreased mature ovarian follicle number ( J:206104 )

♀ • few or no maturing follicles in all mice

absent mature ovarian follicles ( J:206104 )

♀ • few or no maturing follicles in all mice

ovary atrophy ( J:206104 )

♀ • dystrophic/atrophic in 5 of 7 mice

ovary cyst ( J:206104 )

♀ • in 4 of 7 mice

neoplasm

increased intestinal adenoma incidence ( J:206104 )

♀ • gastrointestinal adenomas in 3 of 7 female mice

increased pituitary adenoma incidence ( J:206104 )

♀ • in 5 of 7 female mice

increased Harderian gland tumor incidence ( J:206104 )

♀ • in 3 of 7 female mice

endocrine/exocrine glands

increased pituitary adenoma incidence ( J:206104 )

♀ • in 5 of 7 female mice

increased Harderian gland tumor incidence ( J:206104 )

♀ • in 3 of 7 female mice

abnormal ovary morphology ( J:206104 )

♀ • luteinized stroma in 2 of 7 mice

decreased mature ovarian follicle number ( J:206104 )

♀ • few or no maturing follicles in all mice

absent mature ovarian follicles ( J:206104 )

♀ • few or no maturing follicles in all mice

ovary atrophy ( J:206104 )

♀ • dystrophic/atrophic in 5 of 7 mice

ovary cyst ( J:206104 )

♀ • in 4 of 7 mice

nervous system

increased pituitary adenoma incidence ( J:206104 )

♀ • in 5 of 7 female mice

growth/size/body

ovary cyst ( J:206104 )

♀ • in 4 of 7 mice

digestive/alimentary system

increased intestinal adenoma incidence ( J:206104 )

♀ • gastrointestinal adenomas in 3 of 7 female mice