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Phenotypes Associated with This Genotype
Genotype
MGI:5551815
Allelic
Composition		 Espl1tm1.1Kna/Espl1tm1.2Kna
Wapltm1.1Jmpt/Wapltm1.2Jmpt
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NTac * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Espl1tm1.1Kna mutation (0 available); any Espl1 mutation (92 available)
Espl1tm1.2Kna mutation (0 available); any Espl1 mutation (92 available)
Gt(ROSA)26Sortm9(cre/ESR1)Arte mutation (3 available); any Gt(ROSA)26Sor mutation (1098 available)
Wapltm1.1Jmpt mutation (0 available); any Wapl mutation (169 available)
Wapltm1.2Jmpt mutation (0 available); any Wapl mutation (169 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal mitosis ( J:205429 )
• tamoxifen-treated mouse embryonic fibroblasts exhibit diplo-chromosomes with unseparated arms unlike in control cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory