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Phenotypes Associated with This Genotype
Genotype
MGI:5551813
Allelic
Composition		 Wapltm1.1Jmpt/Wapltm1.2Jmpt
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/6NTac * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm9(cre/ESR1)Arte mutation (3 available); any Gt(ROSA)26Sor mutation (1098 available)
Wapltm1.1Jmpt mutation (0 available); any Wapl mutation (169 available)
Wapltm1.2Jmpt mutation (0 available); any Wapl mutation (169 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell cycle ( J:205429 )
• impaired cell cycle progression in tamoxifen-treated mouse embryonic cells with improper chromosome segregation
abnormal mitosis ( J:205429 )
• tamoxifen-treated mouse embryonic cells exhibit improper chromosome segregation
absent fibroblast proliferation ( J:205429 )
• in tamoxifen-treated mouse embryonic cells stimulated with serum

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory