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Phenotypes Associated with This Genotype
Genotype
MGI:5548131
Allelic
Composition		 Irak2tm1.1Pcoh/?
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irak2tm1.1Pcoh mutation (0 available); any Irak2 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interferon-alpha secretion ( J:205798 )
• from plasmacytoid dendritic cell stimulated with CpG-B, CpG-A or the TLR7 agonist poly(dU)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory