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Phenotypes Associated with This Genotype
Genotype
MGI:5545814
Allelic
Composition		 Lyntm1.1Calo/Lyntm1.1Calo
Myd88tm1Defr/Myd88tm1Defr
Tg(Itgax-cre)1-1Reiz/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyntm1.1Calo mutation (0 available); any Lyn mutation (64 available)
Myd88tm1Defr mutation (4 available); any Myd88 mutation (50 available)
Tg(Itgax-cre)1-1Reiz mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:200745 )
N
• inflammation seen in mutant mice wild-type for Myd88 is reversed and mice do not develop autoantibodies

renal/urinary system
renal/urinary system phenotype ( J:200745 )
N
• kidneys are of normal size and cellularity and show no signs of inflammation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory