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Phenotypes Associated with This Genotype
Genotype
MGI:5544315
Allelic
Composition		 Tbkbp1tm1Aki/Tbkbp1tm1Aki
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tbkbp1tm1Aki mutation (0 available); any Tbkbp1 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:204786 )
N
• macrophages and GM-CSF-derived bone marrow-derived dendritic cells exhibit normal cytokine responses after retinoic acid-induction gene-I-like receptor (RLR) and TLR stimulation
• bone marrow cells proliferate normally in GM-CSF culture

immune system
immune system phenotype ( J:204786 )
N
• macrophages and GM-CSF-derived bone marrow-derived dendritic cells exhibit normal cytokine responses after retinoic acid-induction gene-I-like receptor (RLR) and TLR stimulation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory