Phenotypes Associated with This Genotype

Genotype
MGI:5544201

• Allelic Composition: Trp53^tm1Brn/Trp53^tm1Brn
• Genetic Background: involves: 129P2/OlaHsd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

ovary cyst ( J:200783 )

♀ • 2 of 7 mice injected with an adenovirus expressing cre recombinase into the bursa develop bursal cysts 6 months after injection

♀ • however, mice injected with an adenovirus expressing cre recombinase into the oviduct exhibit no change in phenotype 3 months after injection

ovary degeneration ( J:200783 )

♀ • 2 of 7 mice injected with an adenovirus expressing cre recombinase into the bursa exhibit ovary degeneration 6 months after injection

reproductive system

ovary cyst ( J:200783 )

♀ • 2 of 7 mice injected with an adenovirus expressing cre recombinase into the bursa develop bursal cysts 6 months after injection

♀ • however, mice injected with an adenovirus expressing cre recombinase into the oviduct exhibit no change in phenotype 3 months after injection

ovary degeneration ( J:200783 )

♀ • 2 of 7 mice injected with an adenovirus expressing cre recombinase into the bursa exhibit ovary degeneration 6 months after injection

growth/size/body

ovary cyst ( J:200783 )

♀ • 2 of 7 mice injected with an adenovirus expressing cre recombinase into the bursa develop bursal cysts 6 months after injection

♀ • however, mice injected with an adenovirus expressing cre recombinase into the oviduct exhibit no change in phenotype 3 months after injection